Here you can learn the basic principles of LightDock framework, as well as important details that can help you on your modeling.
A quick guide about how to setup a protein docking simulation with LightDock.
The use of information to drive the modeling has been extensively demonstrated to increase the success of your simulation.
It is now possible to include data in the form of residue restraints during the optimisation protocol of LightDock.
A quick guide about how to setup a protein-DNA docking simulation with LightDock. We also demonstrate the use of information for modeling protein-DNA interactions.
- Transmembrane docking (work in progress)
We are currently working on the development of a protocol to model membrane-associated protein complexes, making use of an implicit representation of the membrane.